In this chapter, we’ll take a look at some of the methods by which CBD is administered. We’ll discuss some of the factors involved in determining dosage.
Bioavailability of CBD Oil
Not all methods of administering CBD are equal. Their effectiveness depends not only on the method of consumption and the ingredients in the product, but also the bioavailability of the CBD afforded by each method.
The bioavailability of any active compound is the percentage of a given dosage that ends up in the bloodstream and is thus available for your body to use.
In the case of CBD oil, the active ingredients include both cannabinoids and terpenes. However, for the sake of discussion, we’ll talk only about the bioavailability of CBD itself.
A bioavailability of 100 percent would signify that 100 percent of the CBD in the product is available to your body. The only way to achieve 100 percent bioavailability is through intravenous administration — meaning injection directly into the bloodstream.
Every other method of consumption will result in some percentage of the CBD becoming unavailable to the body for various reasons, such as becoming trapped in fatty tissues or metabolized (broken down) before it has a chance to enter the bloodstream.
How Long Does CBD Oil Take to Take Effect?
There are several important factors that come into play when determining the onset time of various methods of administration of CBD oil. Some of these variables are related to CBD itself, and others are related to how the human body reacts to CBD.
Because of unique genetics, no two people react to CBD oil in the same way. Furthermore, factors such as age, health, weight, circulation and metabolism can all affect the onset time of the effects of CBD oil.
A factor that can be influenced by all of the above is the number of cannabinoid receptors in the body, how they are expressed, and the ability of the body to produce endocannabinoids. An individual who expresses more receptors or produces fewer endocannabinoids may be more sensitive to CBD than someone with an abundance of endocannabinoids or a lack of receptors.
There are also numerous other factors involved such as the type of product being used, how it’s being used and how much is being used. The onset of edibles will typically be longer than that of tinctures, for example.
The onset time of inhaled CBD is virtually instantaneous. The onset time of edibles and capsules can range anywhere from 20 minutes to over an hour. And the onset time of tinctures can take up to 20 minutes.
These figures are to be considered general guidelines and will vary from person to person, as we mentioned above.
CBD Oil Dosage Recommendations
As with bioavailability and onset time, the ideal dosage of CBD depends on a variety of factors including the product being used, the concentration of the CBD in the product, genetic makeup, sex, weight and so on.
Some CBD products list a recommended serving size. However, without taking into account all of the variables, the recommended serving size might be far too low or possibly even too high. In particular, the serving size will vary greatly depending on the condition for which the CBD is being consumed.
A dosage that is appropriate for one product might be much different than that of a similar product. This is because various CBD oil products contain varying percentages of CBD. Whereas one product might contain 10 percent CBD, another might contain twice that concentration.
The most important factor to be considered, however, is that both dosage and duration of use depend largely on the reason the individual is using it. One person might simply be using CBD as a supplement to support health and wellness, while another might be using CBD for a particular ailment.
Another factor to be considered is whether or not the product being used contains a full or broad spectrum CBD oil with terpenes. For example, a terpene known as myrcene is known to make the brain-blood barrier more permeable, effectively reducing the required dosage for brain conditions.
Given all of the above-listed factors, determining your ideal dosage requires some thinking. Taking too little will not produce the desired effect and will be a waste of time and money. Alternatively, taking more than you need may not provide additional benefits.
It will take some research and experimentation to determine an ideal dosage for a particular person. Good practice is to base your CBD dose on your body weight. Take 1 to 6 mg per 10 pounds of body weight. This chart will help you find the right dosage quicker.
Can You Take Too Much CBD Oil?
CBD is completely non-toxic. Research into CBD’s effects on the human body has shown that CBD is well-tolerated in humans. You would have to consume quite a bit of CBD oil before it results in any truly adverse health effects. There is no known record of anyone ever being poisoned by or overdosing on, CBD.
However, taking more CBD than needed might cause some unwanted effects such as making you too relaxed for particular activities like work or sports.
Once you have arrived at a particular dosage based on the product you are using, it’s a good idea to stick with that product.